• 30 kwietnia, 2021
chikwadrat

Deregulacja mikroRNA w hipertrofii i kostnieniu

Deregulacja mikroRNA w hipertrofii i kostnieniu Ligamentum Flavum: nowe postępy, wyzwania i potencjalne kierunki 

Pathological adjustments within the ligamentum flavum (LF) will be outlined as a means of power progressive aberrations within the nature and construction of ligamentous tissues characterised by elevated thickness, decreased elasticity, native calcification, or aggravated ossification, which can trigger extreme myelopathy, radiculopathy, or each. Hypertrophy of ligamentum flavum (HLF) and ossification of ligamentum flavum (OLF) are clinically frequent entities. Although gathered proof has indicated each genetic and environmental elements may contribute to the initiation and development of HLF/OLF, the particular pathogenesis stays absolutely unclear. MicroRNAs (miRNAs), one of many necessary epigenetic modifications, are brief single-stranded RNA molecules that regulate protein-coding gene expression at posttranscriptional stage, which may disclose the mechanism underlying ailments, determine useful biomarkers, and discover potential therapeutic targets.

Contemplating that miRNAs play a central function in regulating gene expression, we summarized present research from the viewpoint of miRNA-related molecular regulation networks in HLF/OLF. Exploratory research revealed a wide range of miRNA expression profiles and recognized a battery of upregulated and downregulated miRNAs in OLF/HLF sufferers via microarray datasets or transcriptome sequencing. Experimental research validated the roles of particular miRNAs (e.g., miR-132-3p, miR-199b-5p in OLF, miR-155, and miR-21 in HLF) in regulating fibrosis or osteogenesis differentiation of LF cells and associated goal genes or molecular signaling pathways. Lastly, we mentioned the views and challenges of miRNA-based molecular mechanism, diagnostic biomarkers, and therapeutic targets of HLF/OLF.

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Rat Stomach 2 Months Total Protein

RT-302-M2 1mg
EUR 177

Rat Stomach 6 Months Total Protein

RT-302-M6 1mg
EUR 177

Rat Stomach 1 Month Total Protein

RT-302-M1 1mg
EUR 177

Mouse CD1 Stomach, whole Total RNA

MR-302 0.1mg
EUR 160

Mouse C57 Stomach, whole Total RNA

MR-302-C57 0.1mg
EUR 180

Mouse Balbc Stomach, whole Total RNA

MR-302-BLC 0.1mg
EUR 180

Total RNA - Mouse Normal Tissue: Stomach

R1334248-50 50 ug
EUR 156

Cat Stomach Total RNA

FR-302 0.1mg
EUR 195

Human Stomach Total RNA

HR-302 0.05mg
EUR 172

Total RNA - Lupus: Stomach

R1236248Lup-50 50 ug
EUR 460

Sheep Stomach Total RNA

SR-302 0.1mg
EUR 160

Bovine Stomach Total RNA

BR-302 0.1mg
EUR 160

Equine Stomach Total RNA

ER-302 0.1mg
EUR 195

Rabbit Stomach Total RNA

TR-302 0.1mg
EUR 160

Hamster Stomach Total RNA

AR-302 0.1mg
EUR 160

MiniPig Stomach Total RNA

NR-302 0.1mg
EUR 231

Monkey Stomach Total RNA, Rhesus

UR-302 0.1mg
EUR 195

Monkey Stomach Total RNA, Cynomolgus

KR-302 0.1mg
EUR 195

Rat Stomach, whole Total RNA

RR-302 0.1mg
EUR 160

Guinea Pig Stomach Total RNA

GR-302 0.1mg
EUR 160

Total RNA - Diabetic Disease: Stomach

R1236248Dia-50 50 ug
EUR 460

Tissue, Total RNA, Mouse, Adult Normal, Stomach, BioGenomics

MBS638732-005mg 0.05mg
EUR 435

Tissue, Total RNA, Mouse, Adult Normal, Stomach, BioGenomics

MBS638732-5x005mg 5x0.05mg
EUR 1735

Rat WS Stomach, whole Total RNA

RR-302-WS 0.1mg
EUR 160

Total RNA - Rat Normal Tissue: Stomach

R1434248-50 50 ug
EUR 251

Total RNA - Human Tumor Tissue: Stomach

R1235248-50 50 ug
EUR 480

Total RNA - Monkey (Rhesus) Normal Tissue: Stomach

R1534248-50 50 ug
EUR 229

Total RNA - Monkey (Cynomolgus) Normal Tissue: Stomach

R1534248-Cy 50 ug
EUR 229

Tissue, Total RNA, Human Adult Normal, Stomach, Corpus of Stomach, BioGenomics

MBS638709-001mg 0.01mg
EUR 485

Tissue, Total RNA, Human Adult Normal, Stomach, Corpus of Stomach, BioGenomics

MBS638709-5x001mg 5x0.01mg
EUR 1960

Tissue, Total RNA, Human Adult Normal, Stomach, Fundus of Stomach, BioGenomics

MBS638710-001mg 0.01mg
EUR 485

Tissue, Total RNA, Human Adult Normal, Stomach, Fundus of Stomach, BioGenomics

MBS638710-5x001mg 5x0.01mg
EUR 1960

Tissue, Total RNA, Human Adult Normal, Stomach, Cardia of stomach, BioGenomics

MBS638718-001mg 0.01mg
EUR 485

Tissue, Total RNA, Human Adult Normal, Stomach, Cardia of stomach, BioGenomics

MBS638718-5x001mg 5x0.01mg
EUR 1960

Tissue, Total RNA, Human Adult Normal, Stomach, Pylorus of stomach, BioGenomics

MBS638566-001mg 0.01mg
EUR 485

Tissue, Total RNA, Human Adult Normal, Stomach, Pylorus of stomach, BioGenomics

MBS638566-5x001mg 5x0.01mg
EUR 1960

Total RNA - Human Adult Normal Tissue: Stomach

R1234248-50 50 ug
EUR 221

Mouse CD1 Stomach, whole Total Protein

MT-302 1mg
EUR 153

Mouse BLC Stomach, whole Total Protein

MT-302-BLC 1mg
EUR 180

Mouse C57 Stomach, whole Total Protein

MT-302-C57 1mg
EUR 180

Tissue, Total RNA, Human Tumor, Stomach, BioGenomics

MBS638722-005mg 0.05mg
EUR 655

Tissue, Total RNA, Human Tumor, Stomach, BioGenomics

MBS638722-5x005mg 5x0.05mg
EUR 2735

Total Protein - Mouse Normal Tissue: Stomach

P1334248 1 mg
EUR 216

Rat Skin 3 Months Total Protein

RT-101-M3 1mg
EUR 177

Rat Lung 3 Months Total Protein

RT-601-M3 1mg
EUR 177

Rat Brain 3 Months Total Protein

RT-201-M3 1mg
EUR 177

Rat Liver 3 Months Total Protein

RT-314-M3 1mg
EUR 177

Rat Ovary 3 Months Total Protein

RT-406-M3 1mg
EUR 177

Rat Heart 3 Months Total Protein

RT-801-M3 1mg
EUR 177

Rat Testis 3 Months Total Protein

RT-401-M3 1mg
EUR 177

Total RNA - Human Adult Normal Tissue: Stomach: Cardia

R1234250-10 10 ug
EUR 221

Total RNA - Human Adult Normal Tissue: Stomach: Corpus

R1234251-10 10 ug
EUR 221

Total RNA - Human Adult Normal Tissue: Stomach: Fundus

R1234252-10 10 ug
EUR 221

Total RNA - Human Adult Normal Tissue: Stomach: Pylorus

R1234253-10 10 ug
EUR 221

Rat Intestine 3 Months Total Protein

RT-306-M3 1mg
EUR 177

Tissue, Total RNA, Rat Adult Normal, Stomach, BioGenomics

MBS638527-005mg 0.05mg
EUR 505

Tissue, Total RNA, Rat Adult Normal, Stomach, BioGenomics

MBS638527-5x005mg 5x0.05mg
EUR 2060

Tissue, Total RNA, Human Adult Normal, Stomach, BioGenomics

MBS638608-005mg 0.05mg
EUR 495

Tissue, Total RNA, Human Adult Normal, Stomach, BioGenomics

MBS638608-5x005mg 5x0.05mg
EUR 1995

Tissue, Total RNA, Human Disease, Lupus, Stomach, BioGenomics

MBS638737-005mg 0.05mg
EUR 655

Tissue, Total RNA, Human Disease, Lupus, Stomach, BioGenomics

MBS638737-5x005mg 5x0.05mg
EUR 2735

Tissue, Total RNA, Monkey (Rhesus) Adult Normal, Stomach, BioGenomics

MBS638575-005mg 0.05mg
EUR 485

Tissue, Total RNA, Monkey (Rhesus) Adult Normal, Stomach, BioGenomics

MBS638575-5x005mg 5x0.05mg
EUR 1960

Tissue, Total Protein, Mouse Adult Normal, Stomach

MBS657113-1mg 1mg
EUR 565

Tissue, Total Protein, Mouse Adult Normal, Stomach

MBS657113-5x1mg 5x1mg
EUR 2315

Rat S. Muscles 3 Months Total Protein

RT-102-M3 1mg
EUR 177

Dog Stomach Total Protein

DT-302 1mg
EUR 176

Cat Stomach Total Protein

FT-302 1mg
EUR 176

Pig Stomach Total Protein

PT-302 1mg
EUR 153

Rat Stomach 3 Weeks Total Protein

RT-302-W3 1mg
EUR 177

Human Stomach Total Protein

HT-302 1mg
EUR 176

Sheep Stomach Total Protein

ST-302 1mg
EUR 153

Total RNA - Human Adult Normal Tissue 5 Donor Pool: Stomach

R1234248-P 50 ug
EUR 443

Bovine Stomach Total Protein

BT-302 1mg
EUR 153

Equine Stomach Total protein

ET-302 1mg
EUR 176

Rabbit Stomach Total Protein

TT-302 1mg
EUR 153

Hamster Stomach Total Protein

AT-302 1mg
EUR 153

MiniPig Stomach Total Protein

NT-302 1mg
EUR 176

Monkey Stomach Total Protein, Rhesus

UT-302 1mg
EUR 176

Rat Skin 12 Months Total Protein

RT-101-M12 1mg
EUR 177

Rat Skin 2 Months Total Protein

RT-101-M2 1mg
EUR 177

Rat Skin 6 Months Total Protein

RT-101-M6 1mg
EUR 177

Rat Lung 12 Months Total Protein

RT-601-M12 1mg
EUR 177

Rat Lung 2 Months Total Protein

RT-601-M2 1mg
EUR 177

Rat Lung 6 Months Total Protein

RT-601-M6 1mg
EUR 177

Rat Brain 12 Months Total Protein

RT-201-M12 1mg
EUR 177

Rat Brain 2 Months Total Protein

RT-201-M2 1mg
EUR 177

Rat Brain 6 Months Total Protein

RT-201-M6 1mg
EUR 177

Rat Liver 12 Months Total Protein

RT-314-M12 1mg
EUR 177

Rat Liver 2 Months Total Protein

RT-314-M2 1mg
EUR 177

Rat Liver 6 Months Total Protein

RT-314-M6 1mg
EUR 177

Rat Ovary 12 Months Total Protein

RT-406-M12 1mg
EUR 177

Rat Ovary 2 Months Total Protein

RT-406-M2 1mg
EUR 177

Rat Ovary 6 Months Total Protein

RT-406-M6 1mg
EUR 177

Rat Heart 12 Months Total Protein

RT-801-M12 1mg
EUR 177

Rat Heart 2 Months Total Protein

RT-801-M2 1mg
EUR 177

Rat Heart 6 Months Total Protein

RT-801-M6 1mg
EUR 177

Rat Testis 12 Months Total Protein

RT-401-M12 1mg
EUR 177

Rat Testis 2 Months Total Protein

RT-401-M2 1mg
EUR 177

Rat Testis 6 Months Total Protein

RT-401-M6 1mg
EUR 177

Monkey Stomach Total Protein, Cynomolgus

KT-302 1mg
EUR 176

Rat Intestine 12 Months Total Protein

RT-306-M12 1mg
EUR 177

Rat Intestine 2 Months Total Protein

RT-306-M2 1mg
EUR 177

Rat Intestine 6 Months Total Protein

RT-306-M6 1mg
EUR 177

Rat Stomach E20 Total Protein

RT-302-20 1mg
EUR 177

Rat Stomach, whole Total Protein

RT-302 1mg
EUR 153

Guinea Pig Stomach Total Protein

GT-302 1mg
EUR 153

Human Stomach Lysate, Total Protein

Stomach-004H 100ug
EUR 158.4
Description: Stored at -80 centigrade.

Rat S. Muscles 12 Months Total Protein

RT-102-M12 1mg
EUR 177

Rat S. Muscles 2 Months Total Protein

RT-102-M2 1mg
EUR 177

Rat S. Muscles 6 Months Total Protein

RT-102-M6 1mg
EUR 177

Matched Pair - Total RNA - Human Primary Tumor and Normal Tissue: Stomach

R8235248-PP-10 2x10 ug
EUR 500

Rat Stomach 1 Day Total Protein

RT-302-D1 1mg
EUR 177

Rat Stomach 1 Week Total Protein

RT-302-W1 1mg
EUR 177

Rat Stomach 2 Weeks Total Protein

RT-302-W2 1mg
EUR 177

Rat WS Stomach, whole Total Protein

RT-302-WS 1mg
EUR 153

Matched Pair - Total RNA - Human Primary and Metastatic Tumor Tissue: Stomach

R8235248-PM-10 2x10 ug
EUR 773

Total Protein - Human Tumor Tissue: Stomach

P1235248 1 mg
EUR 357

Tissue, Total Protein, Human Tumor, Stomach

MBS657334-1mg 1mg
EUR 680

Tissue, Total Protein, Human Tumor, Stomach

MBS657334-5x1mg 5x1mg
EUR 2835

Tissue, Total RNA Matched Pairs, Human Primary Tumor and Normal, Stomach, BioGenomics

MBS638617-2x001mg 2x0.01mg
EUR 750

Tissue, Total RNA Matched Pairs, Human Primary and Metastasis Tumor, Stomach, BioGenomics

MBS638620-2x001mg 2x0.01mg
EUR 985

Total Protein - Human Adult Normal Tissue: Stomach

P1234248 1 mg
EUR 216

Tissue, Total Protein, Human Adult Normal, Stomach

MBS657318-1mg 1mg
EUR 565

Tissue, Total Protein, Human Adult Normal, Stomach

MBS657318-5x1mg 5x1mg
EUR 2315

Tissue, Total Protein, Human Disease, Diabetes, Stomach

MBS657368-1mg 1mg
EUR 820

Tissue, Total Protein, Human Disease, Diabetes, Stomach

MBS657368-5x1mg 5x1mg
EUR 3470

Total Protein - Human Diabetic Diseased Tissue: Stomach

P1236248Dia 1 mg
EUR 542

Total Protein - Human Adult Normal Tissue: Stomach: Cardia

P1234250 1 mg
EUR 216

Total Protein - Human Adult Normal Tissue: Stomach: Corpus

P1234251 1 mg
EUR 216

Total Protein - Human Adult Normal Tissue: Stomach: Fundus

P1234252 1 mg
EUR 216

Tissue, Total Protein, Human Adult Normal, Stomach, Corpus

MBS657372-1mg 1mg
EUR 565

Tissue, Total Protein, Human Adult Normal, Stomach, Corpus

MBS657372-5x1mg 5x1mg
EUR 2315

Tissue, Total Protein, Human Adult Normal, Stomach, Cardia

MBS657595-1mg 1mg
EUR 565

Tissue, Total Protein, Human Adult Normal, Stomach, Cardia

MBS657595-5x1mg 5x1mg
EUR 2315

Tissue, Total Protein, Human Adult Normal, Stomach, Fundus

MBS657608-1mg 1mg
EUR 565

Tissue, Total Protein, Human Adult Normal, Stomach, Fundus

MBS657608-5x1mg 5x1mg
EUR 2315

Total Protein - Human Adult Normal Tissue: Stomach: Pylorus

P1234253 1 mg
EUR 216

Tissue, Total Protein, Human Adult Normal, Stomach, Pylorus

MBS657527-1mg 1mg
EUR 565

Tissue, Total Protein, Human Adult Normal, Stomach, Pylorus

MBS657527-5x1mg 5x1mg
EUR 2315

Rat Stomach Developmental Total Protein Panel, any 6 stages

RT-302-006D 6x0.1mg
EUR 998

Rat Stomach Developmental Total Protein Panel, any 10 stages

RT-302-010D 10x0.1mg
EUR 1289

Tissue, Total Protein, Matched Pairs, Human Primary Tumor and Normal, Stomach

MBS657350-2x02mg 2x0.2mg
EUR 935

Dog Stomach RNA

DR-302 0.1mg
EUR 195

Mouse Stomach, match set of RNA, DNA, Protein

MS-302-RDP 20µg/20µg/100µg
EUR 422

Matched Pair - Total Protein - Human Primary Tumor and Normal Tissue (PP): Stomach

P8235248-PP 0.2 mg x2
EUR 716

Tissue, Total Protein, Matched Pairs, Human Primary Tumor and Metastasis Tumor, Stomach

MBS657320-2x02mg 2x0.2mg
EUR 1655

Matched Pair - Total Protein - Human Primary Tumor and Metastatic Tumor Tissue (PM): Stomach

P8235248-PM 0.2 mg x2
EUR 1431

Mouse Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells

2-82088 1 Kit Ask for price

Mouse Stomach Genomic DNA

MG-302 0.1mg
EUR 177

Mouse Stomach Tissue Lysate

IMSSTTL100UG each
EUR 245
Description: Mouse Stomach Tissue Lysate

Mouse Stomach Tissue Lysate

MBS8420887-01mg 0.1mg
EUR 385

Mouse Stomach Tissue Lysate

MBS8420887-5x01mg 5x0.1mg
EUR 1540

Tissue Set, BioAssay, DNA, RNA, Protein, Mouse Adult Normal, Stomach

MBS640963-1Set 1Set
EUR 650

Tissue Set, BioAssay, DNA, RNA, Protein, Mouse Adult Normal, Stomach

MBS640963-5x1Set 5x1Set
EUR 2970

Mouse Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells Growth Medium

9-32088 5 x 100 ml Ask for price

Mouse Stomach Tissue Preparation Buffer: Normal Stomach Mucosa Epithelial Cells

9-80202 1 x 100 ml Ask for price

CD-1 Mouse Stomach Cells

ABC-TC3312 1 vial Ask for price
Description: Mouse Primary Cells from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Cells are negative for bacteria, yeast, fungi, and mycoplasma. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

BALB/c Mouse Stomach Cells

ABC-TC3105 1 vial Ask for price
Description: Mouse Primary Cells from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Cells are negative for bacteria, yeast, fungi, and mycoplasma. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

C57BL/6 Mouse Stomach Cells

ABC-TC3247 1 vial Ask for price
Description: Mouse primary stomach cells (MPSTCs) are isolated from tissue of pathogen-free laboratory mice. Mouse primary stomach cells are grown in tissue culture plate pre-coated with 0.2% gelatin for 0.5 hour and incubated in Culture Complete Growth Medium generally for 3-7 days.Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Cells are negative for bacteria, yeast, fungi, and mycoplasma. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

Mouse CD1 Stomach, whole cDNA

MD-302 30 reactions
EUR 243

Mouse BLC Stomach, whole cDNA

MD-302-BLC 30 reactions
EUR 280

Mouse C57 Stomach, whole cDNA

MD-302-C57 30 reactions
EUR 280

Mouse C57 Stomach Genomic DNA

MG-302-C57 0.1mg
EUR 210

Mouse Stomach Whole tissue lysate

MAL-1415 1 mg
EUR 628.8

Fenotypowe i epigenetyczne adaptacje limfocytów T CD4 + krwi pępowinowej do otyłości u matki 

Pregravid weight problems has been proven to disrupt the event of the offspring’s immune system and improve susceptibility to an infection. Whereas the mechanisms underlying the impression of maternal weight problems on fetal myeloid cells are rising, the results for T cells stay poorly outlined. On this examine, we collected umbilical twine blood samples from infants born to lean moms and moms with weight problems and profiled CD4 T cells utilizing move cytometry and single cell RNA sequencing at resting and following ex vivo polyclonal stimulation. We report that maternal weight problems is related to greater frequencies of reminiscence CD4 T cells suggestive of in vivo activation. Furthermore, single cell RNA sequencing revealed enlargement of an activated subset of reminiscence T cells with maternal weight problems.

Nevertheless, ex vivo stimulation of purified CD4 T cells resulted in poor cytokine responses, suggesting useful defects. These phenotypic and useful aberrations correlated with methylation and chromatin accessibility adjustments in loci related to lymphocyte activation and T cell receptor signaling, suggesting a attainable hyperlink between maternal obesogenic surroundings and fetal immune reprogramming. These observations supply a possible clarification for the elevated susceptibility to microbial an infection in infants born to moms with weight problems.

NIEDOBÓR MELOIDNYCH BIAŁEK PHD POGARSZA ATEROGENEZĘ POPRZEZ APOPTOZĘ MAKROFAGOWĄ I SYGNALIZACJĘ WŁÓKNIKA PARAKRYNOWEGO: Miażdżycowe skutki knockdownu PHD szpiku 

Goals: Atherosclerotic plaque hypoxia is detrimental for macrophage perform. Prolyl hydroxylases (PHDs) provoke mobile hypoxic responses, presumably influencing macrophage perform in plaque hypoxia. Thus, we aimed to elucidate the function of myeloid PHDs in atherosclerosis.

Strategies & outcomes: Myeloid particular PHD knockout (PHDko) mice had been obtained through bone marrow transplantation (PHD1ko, PHD3ko) or conditional knockdown via lysozyme M-driven Cre recombinase (PHD2cko). Mice had been fed excessive ldl cholesterol weight loss plan for 6-12 weeks to induce atherosclerosis. Aortic root plaque dimension was considerably augmented 2.6-fold in PHD2cko, and 1.4-fold in PHD3ko in comparison with controls, however was unchanged in PHD1ko mice. Macrophage apoptosis was promoted in PHD2cko and PHD3ko mice in vitro and in vivo, through the HIF1α/BNIP3 axis. Bulk and single cell RNA information of PHD2cko bone-marrow-derived macrophages (BMDM) and plaque macrophages, respectively, confirmed enhanced HIF1α/BNIP3 signaling, which was validated in vitro by siRNA silencing.

Human plaque BNIP3 mRNA was positively related to plaque necrotic core dimension, suggesting related pro-apoptotic results in human. Additional, PHD2cko plaques displayed enhanced fibrosis, whereas macrophage collagen breakdown by matrix metalloproteinases, collagen manufacturing and proliferation had been unaltered. As an alternative, PHD2cko BMDMs enhanced fibroblast collagen secretion in a paracrine method. In silico evaluation of macrophage-fibroblast communication predicted SPP1 (osteopontin) signaling as regulator, which was corroborated by enhanced plaque SPP1 protein in vivo. Elevated SPP1 mRNA expression upon PHD2cko was preferentially noticed in foamy plaque macrophages expressing “triggering receptor expressed on myeloid cells-2” (TREM2hi) evidenced by single-cell RNA, however not in neutrophils. This confirmed enhanced fibrotic signaling by PHD2cko macrophages to fibroblasts, in vitro in addition to in vivo.

Conclusion: Myeloid PHD2cko and PHD3ko enhanced atherosclerotic plaque development and macrophage apoptosis, whereas PHD2cko macrophages additional activated collagen secretion by fibroblasts in vitro, probably through paracrine SPP1 signaling via TREM2hi macrophages.

Translational outlook: This examine reveals that myeloid PHD isoforms PHD2 and PHD3 worsen plaque traits and phenotype, reminiscent of plaque dimension, macrophage accumulation, apoptosis, and collagen accumulation in mice. We present each direct results on macrophages and paracrine results of macrophage PHD2 loss on vessel wall fibroblast populations. Broad spectrum-PHD inhibitors, e.g. Roxadustat, are presently being prescribed to power kidney illness sufferers, who’re already in danger for heart problems. When contemplating this examine and the pro-fibrotic and pro-apoptotic results we report, broad PHD inhibition might subsequently be sub-optimal and extra focused PHD inhibition of PHD1 must be thought of.

Zmiana odpowiedzi interferonu typu I jest związana z subkliniczną miażdżycą tętnic u mężczyzn zakażonych wirusem HIV-1 z supresją wirusologiczną 

Background: Given HIV-1 contaminated sufferers have alterations within the sort I interferon (IFN-I) pathway and are additionally at elevated danger of atherosclerosis, we evaluated IFN-I response and subclinical heart problems (CVD) affiliation in HIV-1-infected sufferers.

Strategies: Transcript ranges of IFN-α/β and IFN-stimulated gene (ISG) 56 had been evaluated by RT/Actual-time PCR in PBMCs collected from asymptomatic HIV-1-positive male sufferers at excessive danger of growing CVD (n=34) and wholesome topics (n=21). Stenosis diploma (≥ or < 50%), calcium quantity rating, calcium Agatston rating and myocardial extracellular quantity had been examined by Coronary CT scan. Carotid intima-media thickness (cIMT), Framingham danger rating, atherosclerotic heart problems (ASCVD) and Knowledge Assortment on Antagonistic Results of Anti-HIV Medication (D:A:D) scores had been additionally measured.

Outcomes: Elevated IFN-α, IFN-β and ISG56 ranges had been noticed in all HIV-1-infected males in comparison with wholesome controls (p<0.001 for all genes analysed). HIV-1-infected sufferers with a stenosis diploma ≥50% confirmed greater Framingham danger rating (p=0.019), which was correlated with IFN-β and ISG56 ranges. HIV-1-infected males with enhanced IFN-I ranges and stenosis displayed the next ASCVD calculated danger (p=0.011) and D:A:D (p=0.004). Additionally, there was a pattern towards greater IFN-α and ISG56 mRNA ranges in HIV-1-positive sufferers with an elevated cIMT (p>0.05).

Conclusion: Dysregulation of IFN-I response may take part in the pathogenesis of HIV-associated CVD. This text is protected by copyright. All rights reserved.

AIMP1P2 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV757180 1.0 ug DNA Ask for price

AIMP1 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV625872 1.0 ug DNA
EUR 616.8

E2F8 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV702062 1.0 ug DNA
EUR 540

E4F1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV709562 1.0 ug DNA
EUR 379.2

E2F3P2 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

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E2F4P1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

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IV Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

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HP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV703724 1.0 ug DNA
EUR 540

C5 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

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EUR 540

MS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

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NA Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

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NM Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

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S7 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

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P1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

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CS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV709016 1.0 ug DNA
EUR 379.2

XM Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV756076 1.0 ug DNA Ask for price

XS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV756094 1.0 ug DNA Ask for price

NP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV814304 1.0 ug DNA
EUR 540

DM1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV723184 1.0 ug DNA Ask for price

DWS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV723520 1.0 ug DNA Ask for price

EBM Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV723688 1.0 ug DNA Ask for price

EGI Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV723934 1.0 ug DNA Ask for price

F7R Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV724762 1.0 ug DNA Ask for price

FND Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV725476 1.0 ug DNA Ask for price

UBB Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV716534 1.0 ug DNA
EUR 379.2

WAC Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV716732 1.0 ug DNA
EUR 379.2

AFA Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV718318 1.0 ug DNA Ask for price

AIC Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV718396 1.0 ug DNA Ask for price

AOM Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV718870 1.0 ug DNA Ask for price

ATD Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV719176 1.0 ug DNA Ask for price

GRN Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV710666 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV710834 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV710840 1.0 ug DNA
EUR 379.2

HYI Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV711146 1.0 ug DNA
EUR 379.2

JTB Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV711560 1.0 ug DNA
EUR 379.2

LBH Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV711902 1.0 ug DNA
EUR 379.2

LTF Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV712076 1.0 ug DNA
EUR 379.2

LUM Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV712088 1.0 ug DNA
EUR 379.2

LXN Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV712094 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV712172 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV712178 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV712184 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV712190 1.0 ug DNA
EUR 379.2

MPI Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV712370 1.0 ug DNA
EUR 379.2

NF2 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV712736 1.0 ug DNA
EUR 379.2

NMI Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV712778 1.0 ug DNA
EUR 379.2

OAT Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV712988 1.0 ug DNA
EUR 379.2

OS9 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV713024 1.0 ug DNA
EUR 379.2

JBS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV730198 1.0 ug DNA Ask for price

JPD Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV730204 1.0 ug DNA Ask for price

KFM Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV730354 1.0 ug DNA Ask for price

KMS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV730474 1.0 ug DNA Ask for price

KSS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV730750 1.0 ug DNA Ask for price

KWE Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV730756 1.0 ug DNA Ask for price

LCO Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV730888 1.0 ug DNA Ask for price

GTS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV727150 1.0 ug DNA Ask for price

HMI Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV728380 1.0 ug DNA Ask for price

HPT Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV728728 1.0 ug DNA Ask for price

HTL Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV728974 1.0 ug DNA Ask for price

CHR Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV721174 1.0 ug DNA Ask for price

CMM Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV721408 1.0 ug DNA Ask for price

CNC Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV721456 1.0 ug DNA Ask for price

COP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV721600 1.0 ug DNA Ask for price

CRG Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV721786 1.0 ug DNA Ask for price

CRS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV721798 1.0 ug DNA Ask for price

CSE Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV721840 1.0 ug DNA Ask for price

CTD Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV721924 1.0 ug DNA Ask for price

DCE Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV722338 1.0 ug DNA Ask for price

DDU Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV722362 1.0 ug DNA Ask for price

RGR Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV714308 1.0 ug DNA
EUR 379.2

Sp2 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV715322 1.0 ug DNA
EUR 379.2

Sp2 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV715328 1.0 ug DNA
EUR 379.2

Syk Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV715610 1.0 ug DNA
EUR 379.2

TK1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV715880 1.0 ug DNA
EUR 379.2

TTK Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV716390 1.0 ug DNA
EUR 379.2

GCY Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV726562 1.0 ug DNA Ask for price

PIP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV713474 1.0 ug DNA
EUR 379.2

PTS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV713990 1.0 ug DNA
EUR 379.2

CCT Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV720670 1.0 ug DNA Ask for price

CCV Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV720724 1.0 ug DNA Ask for price

CRP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV703484 1.0 ug DNA
EUR 540

NPL Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV703700 1.0 ug DNA
EUR 540

FGA Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV704108 1.0 ug DNA
EUR 540

NNT Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV704258 1.0 ug DNA
EUR 540

MSD Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV734290 1.0 ug DNA Ask for price

NSX Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV736498 1.0 ug DNA Ask for price

NT3 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV736504 1.0 ug DNA Ask for price

OAP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV736660 1.0 ug DNA Ask for price

OED Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV736708 1.0 ug DNA Ask for price

PIH Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV740320 1.0 ug DNA Ask for price

PRD Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV741574 1.0 ug DNA Ask for price

PRS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV741754 1.0 ug DNA Ask for price

SDU Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV748132 1.0 ug DNA Ask for price

SEA Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV748138 1.0 ug DNA Ask for price

ST2 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV749656 1.0 ug DNA
EUR 686.4

ST3 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV749662 1.0 ug DNA Ask for price

ST4 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV749674 1.0 ug DNA Ask for price

ST8 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV749692 1.0 ug DNA Ask for price

RP6 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV747190 1.0 ug DNA Ask for price

RSS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV747634 1.0 ug DNA Ask for price

S11 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV747688 1.0 ug DNA Ask for price

S12 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV747694 1.0 ug DNA Ask for price

PDR Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV739876 1.0 ug DNA Ask for price

MAA Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV732370 1.0 ug DNA Ask for price

MCO Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV732646 1.0 ug DNA Ask for price

MEB Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV732676 1.0 ug DNA Ask for price

mF4 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV732748 1.0 ug DNA Ask for price

MLS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV733636 1.0 ug DNA Ask for price

MOK Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV733690 1.0 ug DNA Ask for price

MPE Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV733744 1.0 ug DNA Ask for price

HGF Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV701984 1.0 ug DNA
EUR 540

CA8 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV708260 1.0 ug DNA
EUR 379.2

CA8 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV708266 1.0 ug DNA
EUR 379.2

CBS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV708344 1.0 ug DNA
EUR 379.2

CBS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV708350 1.0 ug DNA
EUR 379.2

CGA Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV708674 1.0 ug DNA
EUR 379.2

CKB Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV708758 1.0 ug DNA
EUR 379.2

CRK Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV708992 1.0 ug DNA
EUR 379.2

CRP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV708998 1.0 ug DNA
EUR 379.2

CRP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV709004 1.0 ug DNA
EUR 379.2

DTL Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV709472 1.0 ug DNA
EUR 379.2

EVL Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV709844 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV710252 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV710258 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV710264 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV710270 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV710276 1.0 ug DNA
EUR 379.2

FUZ Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV710294 1.0 ug DNA
EUR 379.2

GIP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV710408 1.0 ug DNA
EUR 379.2

C8A Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV702506 1.0 ug DNA
EUR 540

SLN Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV702974 1.0 ug DNA
EUR 540

LY9 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV703820 1.0 ug DNA
EUR 540

LY9 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV705296 1.0 ug DNA
EUR 540

DUT Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV705464 1.0 ug DNA
EUR 540

NPL Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV705590 1.0 ug DNA
EUR 540

BMF Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV705644 1.0 ug DNA
EUR 540

FTO Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV706004 1.0 ug DNA
EUR 540

MIP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV706508 1.0 ug DNA
EUR 540

AEN Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV707162 1.0 ug DNA
EUR 379.2

AEN Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV707168 1.0 ug DNA
EUR 379.2

AGK Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV707192 1.0 ug DNA
EUR 379.2

ALB Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV707276 1.0 ug DNA
EUR 379.2

ANG Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV707330 1.0 ug DNA
EUR 379.2

ATM Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV707660 1.0 ug DNA
EUR 379.2

BID Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV707852 1.0 ug DNA
EUR 379.2

BMF Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV707876 1.0 ug DNA
EUR 379.2

BMF Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV707882 1.0 ug DNA
EUR 379.2

FTX Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV761758 1.0 ug DNA
EUR 1104

CPP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV759286 1.0 ug DNA
EUR 2148

CPQ Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV759292 1.0 ug DNA
EUR 686.4

TYS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV754918 1.0 ug DNA Ask for price

VCF Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV755578 1.0 ug DNA Ask for price

VDI Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV755614 1.0 ug DNA Ask for price

WSN Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV755992 1.0 ug DNA Ask for price

WT2 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV755998 1.0 ug DNA Ask for price

WTS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV756004 1.0 ug DNA Ask for price

WWS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV756022 1.0 ug DNA Ask for price

XCE Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV756046 1.0 ug DNA Ask for price

XGR Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV756052 1.0 ug DNA Ask for price

XIC Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV756064 1.0 ug DNA Ask for price

TDD Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV750298 1.0 ug DNA Ask for price

THM Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV750406 1.0 ug DNA Ask for price

TOC Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV750682 1.0 ug DNA Ask for price

PB1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV811124 1.0 ug DNA
EUR 379.2

GBL Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV811202 1.0 ug DNA
EUR 379.2

NLP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV811940 1.0 ug DNA
EUR 379.2

DCI Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV812306 1.0 ug DNA
EUR 379.2

RIP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV812624 1.0 ug DNA
EUR 379.2

CFP Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV791318 1.0 ug DNA
EUR 379.2

ECD Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV791504 1.0 ug DNA
EUR 379.2

HBB Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV791768 1.0 ug DNA
EUR 379.2

NLK Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV792182 1.0 ug DNA
EUR 379.2

NMB Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV792188 1.0 ug DNA
EUR 379.2

NMB Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV792194 1.0 ug DNA
EUR 379.2

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